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Jonathan Taylor, IND: Will be the No.1 pick in most leagues. 32 TDs in his first two seasons.
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Derrick Henry, TEN: Coming off foot injury. Had 219 rushing attempts in 8 games last season.
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Christian McCaffrey, CAR: 10 games played in last two years. Still, volume and talent makes him one the first players off the board.
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Austin Ekeler, LAC: Ekeler's been campaigning for someone to help take the load off. 20 TDs in 2021. PPR monster.
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Dalvin Cook, MIN: Three-straight 1100-yard-plus rushing seasons. Only 6 TDs last season.
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Joe Mixon, CIN: Coming off his best season as a pro. 1205 yds and 13 TDs rushing were career highs.
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Najee Harris, PIT: Got all the volume last season. No reason to think this season will be any different.
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Alvin Kamara, NO: Arrest this off-season could lead to a suspension but may not happen until after the season.
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Nick Chubb, CLE: Averaged at least 5 yards per carry in each of his first four seasons. Usage in pass game is lacking.
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Leonard Fournette, TB: Inline for a big season if he can stay healthy. 69 receptions in 2021.
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Saquon Barkley, NYG: New scheme is what Barkley needed. Rookie year (2018) remains his high-water mark.
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James Conner, ARI: 18 TDs in 2021. Virtually no competition. Setup for a big season if he can stay healthy.
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Javonte Williams, DEN: After splitting time almost evenly with Gordon, everyone is looking for Javonte to be the lead back.
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Aaron Jones, GB: Packers could be run-heavy without additions to receiving corps.
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D'Andre Swift, DET: Swift's dual threat ability can land him in the top 10 (PPR) if he remains healthy.
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Elijah Mitchell, SF: Hamstring injury is causing him to miss preseason action. Comes into 2022 as lead back on a run-heavy team.
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Ezekiel Elliott, DAL: More of an RB2 with Tony Pollard demanding more opportunities.
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David Montgomery, CHI: Volume-based back hovering in the middle of RB2 range but lacks upside.
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Cam Akers, LAR: Remarkable recovery from Achilles injury. Expected to be the lead back in 2022.
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Breece Hall, NYJ: 2nd round draft pick that likely will start Week 1. Will share time with Michael Carter.
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Damien Harris, NE: The lead back on a team that had 24 rushing TDs last season. Lack of receiving makes him a better option in Non-PPR leagues.
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J.K. Dobbins, BAL: Coming off ACL injury. Team is being cautious with him during camp. BAL should lead the league in rushing.
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Dameon Pierce, HOU: Marlon Mack released, clears the way for Pierce to start Week 1.
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Travis Etienne, JAC: Foot injury killed rookie season. Should be the lead back with Robinson rehabbing Achilles injury.
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Cordarrelle Patterson, ATL: Age (31) is a concern. Will his rushing be scaled back?
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Josh Jacobs, LV: Could be last year with Raiders. Will still be the lead back as they break-in the rookies.
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Miles Sanders, PHI: Sanders will be a huge discussion point this Summer. Zero rushing TDs was a fluke but volume concerns are real.
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AJ Dillon, GB: 2021 effort in the passing game is huge for his upside.
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Clyde Edwards-Helaire, KC: Battled injuries in Year 1 & 2. Still better than Ronald Jones.
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Rhamondre Stevenson, NE: Better receiver than Harris but will be volatile due to No.2 role.
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Antonio Gibson, WAS: Resigning of McKissic and drafting of rookie doesn't bode well for Gibson's fantasy outlook. More RB2 than RB1.
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Tony Pollard, DAL: Would be an easy RB1 with Zeke out of the picture.
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Devin Singletary, BUF: Likely to split time with Cook. Split role keeps a cap on his upside.
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Rashaad Penny, SEA: Came on strong the last five games of the season. Expected to start Week 1.
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Chase Edmonds, MIA: A better version of Myles Gaskin. Should be the lead back in Miami.
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Kareem Hunt, CLE: Can hold RB2 value when healthy despite playing behind Chubb.
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Melvin Gordon, DEN: Played well last season. Will be a thorn in the side of Javonte Williams.
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Michael Carter, NYJ: Will play second fiddle to Hall but should be involved after decent rookie season.
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Kenneth Walker, SEA: Rookie had a "procedure" mid-way through August. Back by Week 1?
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James Robinson, JAC: Achilles injury in late December. Will likely start the year behind Etienne.
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Jamaal Williams, DET: Not as dynamic as Swift but worth a bench spot.
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Raheem Mostert, MIA: Hasn't shown much in the passing game. Missed most of 2021 with knee issues. Sony Michel waiting in the wings.
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James Cook, BUF: Pass-catching ability should earn him snaps beginning Week 1. Could take over lead role by mid-season.
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Nyheim Hines, IND: No.2 back in Indy has value, especially in PPR leagues.
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Alexander Mattison, MIN: Late-round option due to his immediate rise to RB1 value when Cook is injured.
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Kenneth Gainwell, PHI: Has value given the heavy rushing game plan in Philadelphia. Boston Scott also in the mix.
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Darrell Henderson, LAR: Better suited as the 1B than the 1A. Late-round worthy.
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Rachaad White, TB: Rookie could carve out a role late in the season or with a Fournette injury.
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J.D. McKissic, WAS: Pass-catching option was courted by Buffalo before returning to Washington.
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Mark Ingram, NO: Back in his familiar role as Kamara's backup. Late-round option.
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Brian Robinson Jr., WAS: Terrible shooting incident leaves the rookie's status up in the air.
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Gus Edwards, BAL: Coming off ACL injury. Not expected to be ready Week 1.
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Khalil Herbert, CHI: No.2 behind Montgomery but showed some promise as a rookie.
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D'Onta Foreman, CAR: Decent showing in Tennessee last season. Will battle Chuba Hubbard for snaps.
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Jeff Wilson, SF: RB room loses Sermon and Hasty leaving Wilson and rookie Tyrion Davis-Price.
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Matt Breida, NYG: Daboll familiar with Breida from their time in Buffalo.
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Dontrell Hilliard, TEN: Played well last season with Henry out.
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Isaiah Spiller, LAC: Signing of Sony Michel plus ankle injury has deflated his value.
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Ronald Jones, KC: Losing value to Isiah Pacheco.
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= Upside
= Risk
