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	Brandon Aiyuk lands on PUP WR working his way back from major knee injury By: Doug Orth \| Aug 26 2025, 11:20 pm
49ers placed WR Brandon Aiyuk on the Physically Unable to Perform List. (ESPN - Adam Schefter) FFToday's Take: This has been expected for some time. Aiyuk will miss at least the first four games of the season and possibly more. It is also important that did more than just suffer a clean tear of the ACL. As a result, he could struggle to be the receiver that many remember him being before the injury even after he returns. Fantasy managers are still advised to take him late in drafts and stash him for as long as possible, especially in leagues that allow Aiyuk to sit on IR.

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