Entering training camp, Nelson was expected to challenge for a backup role on a Bills squad lacking depth behind starters Steve Johnson and Lee Evans. However, Evans trade to the Ravens and Marcus Easley’s reported heart condition moved Nelson up the depth chart and he ended the season starting 13 games. A big target at 6’5”, 215 pounds, Nelson has the size to play outside but was used mostly in the slot by the Bills. He played well early, catching 39 passes for 433 yards and four touchdowns over the first nine games of the year. However, he struggled down the stretch, averaging just 4.1 Fpts per game over his final seven contests with just 22 receptions for 225 yards and one touchdown. He shapes up as a WR5/WR6 in 2012.